I have spondylitis and have had lots of joints injected through the years. I never feel quite "right" for about 24hours after, cortisone seems to make me dysphoric. That being said I just figure that is the price I pay for joint relief. I know I am perhaps more sensitive than many others, but since in the end it seems to help, I put up with it.
ihad my shoulder injected about two weeks ago, and it has helped with shoulder pain a great deal.