I read a really good book on the subject several years ago, "My Lobotomy" by Howard Dully. As I recall, he was just a typical boy who acted up sometimes, and he was lobotomized to keep him in check. Horrific.
I am currently reading "Before I Forget" by B. Smith, Dan Gasby & Michael Shnayerson. Apparently Smith and Gasby are celebrities, although I was not familiar with them. She developed Early Onset Alzheimer's Disease, and the story is told by the both of them from their different points of view(I assume Michael did the actual writing). Very good so far.
I'm also reading The Drop by Dennis Lehane. That one is good too, but in a very different way. Sheer entertainment.