I'm on an angiotensin-receptor blocker and a calcium-channel blocker and a diuretic. While all meds have their side effects and contraindications, the first two meds have only minor side effects for me at the doses at which I take them, but I time when I take the diuretic (even at its low dose) because it will require access to a toilet shortly after taking it -- and that's not always easy or even possible. I usually take the diuretic in the mornings when I'm home to manage that side effect, but if I need to get moving as soon as I wake up, I may push taking the diuretic until lunchtime or whenever I'm home from the event. So whoever prescribed it for you may be cognizant of this (IMHO) significant side effect.