Placebo--the very best kind of drug, IMO. No side effects but relief.
To mangle Voltaire "The job of the physician is to keep the patient occupied while the body heals itself."
And i agree that alcohol and opiates are much more destructive. Alcohol seems to be a sacrament among much of the middle class, which bodes no good for future health outcomes. And where opioids face tacit disapproval, alcohol is roundly celebrated.