JP, metformin causes most people to lose weight. I have known people to lose between 50-100 lbs. They considered marketing it as a weight loss drug but didn’t because of the side effects. Some of the other diabetes drugs doctors are using for weight loss but when my friend inquired her doctor wouldn’t prescribe any of them because they also caused muscle loss. So many people are getting diabetes because of all the crap in our food including high fructose syrup. Many things in food are not allowed in Europe.