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iris lilies
12-19-25, 10:56am
Fire questions at me!

I started a weight loss drug a couple of weeks ago. It is a damn miracle! I mean, yowza! It was immediately effective. Food noise—gone. Satiation with small amounts of food—super effective.

Prior to this, i lost 18 lbs and got stuck.I need to drop another 15 or so. This drug makes it possible.

KayLR
12-19-25, 11:44am
Side effects?

frugal-one
12-19-25, 12:29pm
Fire questions at me!

I started a weight loss drug a couple of weeks ago. It is a damn miracle! I mean, yowza! It was immediately effective. Food noise—gone. Satiation with small amounts of food—super effective.

Prior to this, i lost 18 lbs and got stuck.I need to drop another 15 or so. This drug makes it possible.

Is this something you need to take long term? Side effects ?

Alan
12-19-25, 12:32pm
My wife is on her 5th weekly dose and is showing steady, predictable results. She's wondering if you will continue with micro-dosing once you've reached your goal.

Tradd
12-19-25, 12:45pm
I see lots of articles in the NYT that there is promising research about the GLP1 drugs being helpful for other conditions besides weight loss.

frugal-one
12-19-25, 12:51pm
What does the drug deplete from your body. B12, magnesium, calcium? ….worth checking and correcting, if necessary,

iris lilies
12-19-25, 1:26pm
Side effects: none I feel. I am on a low dose, the typical starting dose.

negative side effects are: reduction of muscle mass.. I’m supposed to be doing weightlifting exercises, but I haven’t done much of that.

About B-12: the drug I’m on is a compounded tirzepatide with a B-12 supplement. Tirzepatide is the active ingrediant in Zepbound and Mounjaro. It Operates on two hormones while the semiglutides (Ozempic) just operate on one.

positive results: those mentioned plus it is supposed to reduce inflammation. I don’t have inflammation that is more than the normal amount for someone of my age, so I haven’t noticed any positive effects of that, but Internet chatter has several people noticing their aches and pains are greatly reduced or gone.

iris lilies
12-19-25, 1:28pm
My wife is on her 5th weekly dose and is showing steady, predictable results. She's wondering if you will continue with micro-dosing once you've reached your goal.

boy I think so. I’m already a little worried about growing out of the drug’s effect after long term use.

iris lilies
12-19-25, 1:33pm
Cost: I’m paying for it all out of pocket. my doctor charges $65 per shot and the shots are once a week. I’m experimenting during the holiday season with prolonging the period between shots because her office is closed for 10 days. I go to her office to have the shots because it is so easy, she’s very close and I already pay a flat fee per year for her services so the office visit costs $0.

frugal-one
12-19-25, 2:40pm
Side effects: none I feel. I am on a low dose, the typical starting dose.

negative side effects are: reduction of muscle mass.. I’m supposed to be doing weightlifting exercises, but I haven’t done much of that.

About B-12: the drug I’m on is a compounded tirzepatide with a B-12 supplement. Tirzepatide is the active ingrediant in Zepbound and Mounjaro. It Operates on two hormones while the semiglutides (Ozempic) just operate on one.

positive results: those mentioned plus it is supposed to reduce inflammation. I don’t have inflammation that is more than the normal amount for someone of my age, so I haven’t noticed any positive effects of that, but Internet chatter has several people noticing their aches and pains are greatly reduced or gone.

I do not know what drug you are taking but you would be wise to see what it depletes from your body. BTW inflammation is not normal at any age.

A few years ago my DH had complete kidney failure and he decided to take all the drugs they were pushing on him. So, I researched what each drug depleted from his body and what (organic) foods would replenish. He was told that he is the only person that had a full recovery from a situation such as his. Coincidence, I don’t think so. Food is medicine. Also, most drugs deplete something…..

iris lilies
12-19-25, 3:03pm
I do not know what drug you are taking but you would be wise to see what it depletes from your body. BTW inflammation is not normal at any age.

The drug I am on is tirzepatide + B12.

Many people my age have SOME arthritis, which involves inflammation. I don’t see it in my hands very much…maybe at little bit at times… but I have occasional bouts of gout which is a form of arthritis. I would not say gout
is “normal “but I consider some arthritic joints to be a normal part of aging.

You’re right that most drugs have a side effect and often several side effects, including I suppose depletion of essential nutrients.

Alan
12-19-25, 4:21pm
The drug I am on is tirzepatide + B12.

That's exactly what my wife is taking. As she explained it to me the dosage is graduated over time so her first 4 injections were at a certain dosage and her current (5th) injection and the following 6th, 7th and 8th injections are at a higher dosage level. I'm not sure what happens after that although she tells me that like you, she's considering eventual micro doses to help maintain the success she's had.

pinkytoe
12-19-25, 4:23pm
Is B12 depleted when weight loss drugs are taken? I am too chicken to use any pharmaceuticals but if it works for you, that's great.

iris lilies
12-19-25, 4:30pm
Is B12 depleted when weight loss drugs are taken? I am too chicken to use any pharmaceuticals but if it works for you, that's great.

I do not know if B12 is depleted. From my understanding, EJ Lily owns the patent to tirzepatide and it cannot be sold in pure form by anyone else. So, compounding pharmacies sell this drug with a B12 addition thereby operating within legalities.

iris lilies
12-19-25, 4:31pm
That's exactly what my wife is taking. As she explained it to me the dosage is graduated over time so her first 4 injections were at a certain dosage and her current (5th) injection and the following 6th, 7th and 8th injections are at a higher dosage level. I'm not sure what happens after that although she tells me that like you, she's considering eventual micro doses to help maintain the success she's had.

My doctor said she goes up in dosage when weight loss stops for a month. That seems a bit draconian to me, but I haven’t reached that yet so we shall see.